Over 150 Faculties and 200 PhD scholars, research associates and project staffs are engaged in various frontline research activity in science & technology, Social science, Arts and humanities areas.
Over 150 Faculties and 200 PhD scholars, research associates and project staffs are engaged in various frontline research activity in science & technology, Social science, Arts and humanities areas.
School of Physical and Chemical Science
Department of Chemistry
Computational approach to identify underlying mechanism of herbal drugs
Dr. Amiya Priyam and his research scholar Mr. Bhavesh Kumar Dadhich synthesized a new class of nanomaterials ‘Hollow Silver Nanoshells’, which show unique optical property, ‘surface plasmon resonance’ in the near-IR region. In addition to the treatment of cancer, these nanomaterials can also be utilized to harvest solar energy for environmental remediation of dye-wastes produced in textile industry.
Department of Bioinformatics:
Computational approach to identify underlying mechanism of herbal drugs
In the area of molecular drug design, Professor Rathore in collaboration with scientists at University of Hyderabad has developed a novel method to elucidate underlying mechanism of action of Ayurvedic and herbal drugs. Mankind has consumed traditional Ayurvedic, Unani and various herbal drugs from the time immemorial. The scientific rationale of these drugs has eluded us until yet. The research published in a Wiley Journal of Chemical Biology and Drug Design describe the method that not only identifies the active molecules, but also the underlying mechanism of their action. This opens up a whole range of innumerable possibilities to use traditional natural herbs as starting point to design novel drugs with less or no side effects. This technology has potential to cut down cost and time involved in making a new drug
Research on Breast cancer metastasis
Over 150 Faculties and 200 PhD scholars, research associates and project staffs are engaged in various frontline research activity in science & technology, Social science, Arts and humanities areas.
For details See –
[1]. Potshangbam AM, Polavarapu R, Rathore RS*, Naresh D, Prabhu NP, Potshangbam N, et al. Med PS erver: A database for identification of therapeutic targets and novel leads pertaining to natural products. Chemical Biology & Drug Design (Wiley). 2019;93(4):438–46. https://doi.org/10.1111/cbdd.13430
[2]. The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis Federica Fusella, Laura Seclì, Elena Busso, Anna Krepelova, Enrico Moiso, Stefania Rocca, Laura Conti, Laura Annaratone, Cristina Rubinetto, Maurizia Mello-Grand, Vijay Singh, Giovanna Chiorino, Lorenzo Silengo, Fiorella Altruda, Emilia Turco, Alessandro Morotti, Salvatore Oliviero, Isabella Castellano, Federica Cavallo, Paolo Provero, Guido Tarone & Mara Brancaccio, Nature Communications volume 8, Article number: 1636 (2017)
Chemical Biology and Drug Design
Department of Biotechnology
Use of g-rays to enhance the production of Makhana
The impact of gamma irradiation on growth and physiology of Euryale ferox was described in the present investigation. E. ferox is an underutilized aquatic food crop that grows in shallow-water bodies in lower Assam regions and north Bihar of India. The seeds of E. ferox were irradiated with different doses of gamma irradiation ranging from 0 to 500 Gy. It was observed that the germination and survival percentage was inhibited by increasing the irradiation dose. However, plants developed from seed exposed to an irradiation dose beyond 100 Gy did not survive more than 1 month.
More detail in –
Physiological and biochemical responses of Makhana (Euryale ferox) to gamma irradiation N Kumar, S Rani, G Kuamr, S Kumari, IS Singh, S Gautam, BK Choudhary Journal of biological physics 45 (1), 1-12, 2019.
